What is the 3rd phase of primary TB infection?

What is the 3rd phase of primary TB infection?

• A. Latent TB Infection
• B. Progressive TB / Active Disease
• C. Early Generalization Miliary TB
• D. Cavitary TB

Answer: (B)

In TB, after the initial inhalation and establishment of infection, the body's immune response can either contain the bacilli or fail to do so. If containment succeeds, the bacteria linger in a dormant state, resulting in latent TB infection with no symptoms. The third phase is when containment fails and the infection progresses to active disease, meaning the bacilli multiply and clinical illness develops. This stage is called progressive TB or active disease. It’s the phase where people typically develop symptoms such as a persistent cough, fever, night sweats, and weight loss, and can become contagious. Forms like early generalized miliary TB or cavitary TB are manifestations that can occur once disease is active, but the general third phase refers to the transition from latent infection to active disease.

In TB, after the initial inhalation and establishment of infection, the body's immune response can either contain the bacilli or fail to do so. If containment succeeds, the bacteria linger in a dormant state, resulting in latent TB infection with no symptoms. The third phase is when containment fails and the infection progresses to active disease, meaning the bacilli multiply and clinical illness develops. This stage is called progressive TB or active disease. It’s the phase where people typically develop symptoms such as a persistent cough, fever, night sweats, and weight loss, and can become contagious. Forms like early generalized miliary TB or cavitary TB are manifestations that can occur once disease is active, but the general third phase refers to the transition from latent infection to active disease.